2017

  • Mechanisms of ion transport and segregation of charge during transcranial direct current stimulation (tDCS): a multichannel magnetoencephalographic study

  • Adaption of a manual Toxoplasma gondii IgG ELISA to a fully automated analyzer

  • Optimization of a measurement method for determination of the diffuse performance of low-flux dialysis membranes (polyether sulfone)

  • Force measurements in developing Zebrafish using hydrogel based stress sensors

  • Enzymatic hydroxylation of steroids

  • Identification and characterization of tumor inhibiting and oncogenic micro-RNAs of HCC using in-vitro and in-vivo techniques

  • The relevance of ubiquitin-modified lysine residues in the viral polymerase of the influenza-A-virus on RNA sythesis

  • Optimization, scale-up and economic analysis of the production of β-aspartyl-L-ornithine and β-L-aspartyl-L-citrulline by selective hydrolysis of β-L-aspartyl-L-arginine

  • Development of a Post-Market Surveillance Program for the Root Canal Instruments Product Family as Part of Quality Management

2016

  • Improvement of the sensitivity of a saliva-based THC immunoassay

  • Genotoxic effects in in-vitro nanotoxicology: Application of the alkaline comet assay on fibroblasts after co-culture with alveolar macrophages

  • Factors influencing the effectiveness of fungicidal agents in mold remediation

  • Effect of culture medium and transduction on endothelial phenotype

  • Depletion of SDS/SDC in decellularized porcine heart valves by means of protic solvents

  • Microbiological study about the suitability of mineral preservatives for pan and coating conservation in comparison to conventional preservation methods

2015

  • Evaluation of an automated synthetic micro-dosing method for the reinforcement of polycarbonate-urethane heart valves

  • Magnetoencephalographic examination of the charge distribution induced by directed DC stimulation (tDCS) on a physiological spherical model

  • Safety notifications from clinical trials with medical devices: Comparative analysis of European reporting forms witg regard to the use of drug databases based on the ICH E2B data sets

  • Selection, dimensioning and qualification of a tissue cutting method for medical implants

  • Use of capnovolumetry as a supplementary diagnostic method for pulmonary function testing

  • Development of a strategic concept based on an environmental and company analysis of the hospital communication sector

  • New development of a fatigue test system for examining standard and in vivo tests on ceramic hip joint components

  • Development of a physical method for the determination of the tightness and controlled opening of an original closure of a medical device

  • Investigation of the relationship between different methods for the determination of day drowsiness or vigilance

  • MOF-based nanoparticles as drug delivery systems

 

2014

  • Development of a highly precise microprocessor-controlled thermostat for laser and light emitting diodes in miniaturized analysers

  • Conjugation of spin labelled proteins with fluorescent quantum dots

  • Development of a user interface using Matlab for the automated detection of hearing responses in a "Neural Response Imaging" measurement

  • Comparison of the electrical and magnetic transcranial evoked potentials in patients with compression of spinal motor pathways

  • Physical characterisation of nanoparticles

  • Evaluation of methods for the detection and correction of head movements during the measurements in the entire head neuro magnetometer system (MEG)

  • Fundamental considerations on the design and the mode of operation of valve structures made of thin films

2013

  • Development of a signal processing algorithm for energy efficient Laser Doppler perfusion monitoring

  • Optimisation of the biotinylation of allergens for the use in a BDLiquid System

  • Quantitative detection of elements on the skin in cases of current-induced death in bathtubs

  • Recursive Pitch-Matching

  • Design of a procedure for the determination of the minimum shelf life of medical devices during their development, taking into account the economic factors and the use of these results through product examples

  • Development of a marketing strategy to communicate the changing level basis to in vitro diagnostics manufacturers and within the notified office based on an analysis of the effects of the new regulations (degree programme industrial engineering)

  • Autodisplay of plant cytochrome P450 monooxygenases and characterisation of the obtained whole cell biocatalysts

  • Development of a surgial table for ophthalmology

  • Development of a compact measurement device for the switchSENSE technolgy

  • Analysis of process related solution components in protein containing formulations

  • Development of a three-dimensonal cellular assay for use in high-content screening

  • Development of a method for the enrichment of circulating tumor cells from whole blood and their subsequent isolation on biocompatible hydrogel matrices

  • Optimisation and validation of a STR-multiplex analysis for pigeons

  • Interactions of procaryotic and eucaryotic cells with nanostructured titanium surfaces produced by the glancing angle deposition technique

  • Characterisation of DNA isolation methods for the follow up use of real-time PCR in a point-of-care system

  • Automated growth process monitoring of yeast cells in bioreactors

2012

  • Cell fate of hMSCs in a bottom-up approach for complex 3D engineered tissues

  • Epithelial-mesenchymal interactions during branching morphogenesis in a three-dimensional lung cell culture model

  • Recombinant expression of bacillolysin in Bacillus subtilis

  • Establishment of the analysis of pioglitazone and the validation of the "dried blood spot (DBS)" method in Callithrix jacchus / Macaca fascicularis

2011

  • Detection of gene rearrangements using fluorescent in-situ hybridisation (FISH) in radiation-associated mammary carcinomas

  • The left heart bypass - Use of extracorporeal circulation during operations on the thoracic aorta

  • Development and validation of a partially automated method for water disinfection in hypothermia devices by means of ozone

  • New development and evaluation of a γH2AX-foci-assay by means of the automated evaluation of the AKLIDES® technology and the assembly and design of the corresponding kit

  • Development of segmented tube heating elements for the control of optimized breathing gas temperature

  • Application development for real-time rapid PCR and comparison of manual and automatic liquid handling

  • Development and characterisation of a model system for enzymatic debridement

  • Influence of nanoparticles (dentritic polyglycerol sulfates) and various microfleece fibretopologies on the expression profile and differentiation of cartilage cells with regard to arthrosis therapie

2010

  • Laboratory quality management system for a urology specialist practice

  • Intensified first-sample inspection of the Omnitest 3 blood glucose meter with special regard to its suitability for use

  • Investigation of the feasibility of the impedance measurements with microbial united cell structures

  • Establishment of a data processing software using MS Access for trace analysis in the field of forensic molecular genetics

  • Development of an epidural catheter for short term epidural anaesthesia

  • Transfer of mRNA in respiratory epithelial cells by means of magnetofection

  • Characterisation of HA-based bone replacement material produced by powder injection moulding

  • Qualitative comparison of the minimal extra corporeal circulation system ROCsafeRX from the company Terumo with two conventional extra corporeal circulation systems, considering specific peri- and postoperative parameters during bypass operations

  • Investigations of novel digital holographic microscopy methods for the analysis of living cells

2009

  • Cloning of an allelic ladder for a forensic mtDNA SNP detection method

  • Innovative sampling device for tissue samples of the cervix

  • Investigation of thermal markers

  • Determination of the atrial and ventricular mechanical activity with an implantable sensor

  • Production of 3-D photonic crystals via self-organisation

  • Material tests on medical implants made of nickel-titanium

  • Determination of a correlation between adhesive strength / pH value / release of active substance of a moist self-adhesive film and its chemical compounding

  • Process validation of a titanium injection moulding method based on DIN EN ISO 13485:2003

  • Conception and production of a microfluidic component for sorting droplets

  • Strength analysis of osteosynthesis plates in veterinary medicine

  • Magnetic nanoparticles: Feasibility for biomedical applications

  • Prototype development of a point-of-care system for molecular biology diagnostic of oral infections

  • Microrarray-based DNA polymerase reactions as highly sensitive detection and genotyping tests

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